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cenobamate will decrease the extent or effect of fentanyl transdermal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Improve dose of CYP3A4 substrate, as needed, when coadministered with cenobamate.belzutifan will reduce the level or result of fentanyl transdermal by affecting hepatic/intestinal enzyme C